If the coin is just a proof version of a normal coin it will have the same KM#. But if a coin has been made from a different metal such as Silver or Gold then yes it will have a different KM#.
But sometimes it is just a small difference to the KM# from the normal Coin.
For instance this coin N#87706 is KM# 645
But the silver version N#66274 is KM# 645a
Mike
Master Referee - See my profile for what I collect.